Zyban
(Bupropion
Sustained Release- Oral )

Important
information you should know
USES: This medication is used to help you quit smoking.
HOW TO USE: Swallow this medication whole. Do not crush
or chew them or the sustained activity of the drug will be destroyed
and the chances of side effects occurring may be increased. Take as
directed, usually twice daily for 7 to 12 weeks. Do not take more or
less medication than prescribed. Since this drug can cause sleeplessness
at first, it is best not to take near bedtime. It is advised to continue
smoking for the first week after starting this drug, until it reaches
higher levels in your blood. Do not smoke if using any nicotine products
with this drug. Too much nicotine can cause serious side effects.
SIDE EFFECTS: This medication is generally well tolerated.
Dry mouth, headache, increased sweating, constipation, anxiety and fatigue
may occur. If these effects persist or worsen, notify your doctor.
PRECAUTIONS: Before taking bupropion tell your doctor if you
have a history of seizures, head injury, brain tumor; heart, liver or
kidney disease, an eating disorder or any mental conditions, diabetes
or if you have any allergies. Limit or avoid consumption of alcoholic
beverages; alcohol can increase your risk of seizures. Chronic alcohol
users who suddenly stop the intake of alcohol while taking bupropion
may increase the risk of having seizures. Suddenly stopping certain
tranquilizers (e.g., diazepam, chlordiazepoxide) is not recommended
because doing so may increase the risk of having seizures. Elderly patients
may be more sensitive to the effects of this drug. Tell your doctor
if you are pregnant or plan to become pregnant before taking this drug.
This drug is excreted into breast milk. Because of the potential risk
to the infant, breast-feeding while using this drug is not recommended.
Consult your doctor before breast-feeding.
Do not allow anyone else to take this medication.
DRUG INTERACTIONS: Before taking bupropion tell your
doctor of all nonprescription and prescription medications you may use
especially MAO inhibitors (e.g., isocarboxazid, phenelzine, tranylcypromine,
pargyline, selegiline, furazolidone), levodopa, theophylline, corticosteroids
(e.g., prednisone), seizure medications, sedatives, ritonavir, tranquilizers/psychiatric
drugs (e.g., chlorpromazine), other antidepressants (e.g., amitriptyline),
salicylates (e.g., aspirin, salsalate), isoniazid, chlolinesterase inhibitors
(e.g., tacrine, donepezil), morphine, and adrenaline-like drugs (e.g.,
pseudoephedrine). Excess caffeine intake can increase the chance of
seizures with this drug. Check all nonprescription/prescription drug
labels for caffeine. Consult doctor or pharmacist. A certain product
used to help quit smoking contains bupropion. Do not take that product
while using this one.
MISSED DOSE: Take any missed dose as soon as possible
but not if it is within 8 hours of the next dose. If it is time for
the next dose, skip the missed dose and resume your regular schedule.
Do not "double up" the dose.
STORAGE: Store at room temperature and
keep away from moisture and sunlight. Keep this and all medications
out of the reach of children.
IMPORTANT NOTE:
The following information is intended to supplement,
not substitute for, the expertise and judgment of your physician, pharmacist
or other healthcare professional. It should not be construed to indicate
that use of the drug is safe, appropriate, or effective for you. Consult
your healthcare professional before using this drug.